Genomic characterization and phylogenetic analysis of SARS-COV-2 in Italy

J Med Virol. 2020 Sep;92(9):1637-1640. doi: 10.1002/jmv.25794. Epub 2020 Apr 10.


This report describes the isolation, molecular characterization, and phylogenetic analysis of the first three complete genomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolated from three patients involved in the first outbreak of COVID-19 in Lombardy, Italy. Early molecular epidemiological tracing suggests that SARS-CoV-2 was present in Italy weeks before the first reported cases of infection.

Keywords: COVID-19; complete genomes of SARS-CoV-2; phylogenetic analysis.

MeSH terms

  • COVID-19 / epidemiology*
  • COVID-19 / virology*
  • Computational Biology / methods
  • Genome, Viral*
  • Genomics* / methods
  • Humans
  • Italy / epidemiology
  • Phylogeny*
  • Regression Analysis
  • SARS-CoV-2 / classification*
  • SARS-CoV-2 / genetics*