Asymptomatic and Human-to-Human Transmission of SARS-CoV-2 in a 2-Family Cluster, Xuzhou, China

Emerg Infect Dis. 2020 Jul;26(7):1626-1628. doi: 10.3201/eid2607.200718. Epub 2020 Jun 21.


We report epidemiologic, laboratory, and clinical findings for 7 patients with 2019 novel coronavirus disease in a 2-family cluster. Our study confirms asymptomatic and human-to-human transmission through close contacts in familial and hospital settings. These findings might also serve as a practical reference for clinical diagnosis and medical treatment.

Keywords: 2019 novel coronavirus disease; COVID-19; China; SARS-CoV-2; Xuzhou; asymptomatic transmission; close contact; familial cluster; nosocomial transmission; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.

MeSH terms

  • Adult
  • Asymptomatic Diseases*
  • Betacoronavirus*
  • Coronavirus Infections / transmission*
  • Family
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / transmission*

Supplementary concepts

  • COVID-19
  • severe acute respiratory syndrome coronavirus 2