Forty years with coronaviruses

J Exp Med. 2020 May 4;217(5):e20200537. doi: 10.1084/jem.20200537.

Abstract

I have been researching coronaviruses for more than forty years. This viewpoint summarizes some of the major findings in coronavirus research made before the SARS epidemic and how they inform current research on the newly emerged SARS-CoV-2.

MeSH terms

  • Betacoronavirus* / genetics
  • Betacoronavirus* / pathogenicity
  • COVID-19
  • Coronavirus Infections* / epidemiology
  • Coronavirus* / genetics
  • Coronavirus* / pathogenicity
  • Coronavirus* / physiology
  • Genome
  • Humans
  • Immune Evasion
  • Interprofessional Relations
  • Middle East Respiratory Syndrome Coronavirus / genetics
  • Middle East Respiratory Syndrome Coronavirus / pathogenicity
  • Pandemics
  • Phylogeny
  • Pneumonia, Viral / epidemiology
  • RNA, Viral* / genetics
  • Research / trends
  • SARS-CoV-2
  • Severe acute respiratory syndrome-related coronavirus / genetics
  • Severe acute respiratory syndrome-related coronavirus / pathogenicity
  • Viral Proteins* / physiology
  • Virion
  • Virology / trends

Substances

  • RNA, Viral
  • Viral Proteins