Passive smoking and type 2 diabetes among never-smoking women: The Japan Public Health Center-based Prospective Study

J Diabetes Investig. 2020 Sep;11(5):1352-1358. doi: 10.1111/jdi.13259. Epub 2020 May 24.

Abstract

Aims/introduction: The aim of the current study was to prospectively evaluate the association between passive smoking from a spouse and the risk of diabetes among never-smoking Japanese women. Passive smoking at a workplace (or public facilities) was assessed as a secondary measure.

Materials and methods: In the Japan Public Health Center-based Prospective Study (baseline 1990 or 1993), we followed 25,391 never-smoking women aged 40-69 years and without diabetes. Passive smoking was defined as having a husband who was a self-reported smoker, and the exposure at a workplace (or public facilities) was self-reported by women. The development of diabetes was identified in questionnaires administered at the 5-year and 10-year surveys. A pooled logistic regression model was used to assess the association between passive smoking and the development of diabetes with adjustment for age and possible confounders.

Results: Compared with women whose husbands had never smoked, women whose husband smoked ≥40 cigarettes/day had significantly higher odds of developing diabetes in an age-adjusted model, but the association was attenuated in a multivariable model (odds ratio 1.34, 95% confidence interval 0.96-1.87). There was a dose-response trend between the number of cigarettes smoked by a husband and the odds of developing diabetes (P = 0.02). Women reporting daily passive smoking at a workplace (or public facilities) had higher odds of developing diabetes than women reporting no such exposure (odds ratio 1.23, 95% confidence interval 0.995-1.53).

Conclusions: Our results indicated a higher risk of diabetes among never-smoking Japanese women with higher exposure to passive smoking from a spouse.

Keywords: Diabetes mellitus; Tobacco smoke pollution; Women.

MeSH terms

  • Adult
  • Aged
  • Biomarkers / analysis*
  • Blood Glucose / analysis*
  • Diabetes Mellitus, Type 2 / chemically induced
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Diabetes Mellitus, Type 2 / pathology
  • Female
  • Follow-Up Studies
  • Humans
  • Japan / epidemiology
  • Male
  • Middle Aged
  • Prognosis
  • Prospective Studies
  • Public Health
  • Risk Factors
  • Surveys and Questionnaires
  • Tobacco Smoke Pollution / adverse effects*

Substances

  • Biomarkers
  • Blood Glucose
  • Tobacco Smoke Pollution