The Glue that Binds Us: The Hunt for the Molecular Basis for Multicellularity

W James Nelson

doi:10.1016/j.cell.2020.03.017

The Glue that Binds Us: The Hunt for the Molecular Basis for Multicellularity

Cell. 2020 Apr 30;181(3):495-497. doi: 10.1016/j.cell.2020.03.017. Epub 2020 Mar 31.

Author

W James Nelson¹

Affiliation

¹ Department of Biology, Stanford University, Stanford, CA 94305, USA. Electronic address: wjnelson@stanford.edu.

PMID: 32234519
DOI: 10.1016/j.cell.2020.03.017

Abstract

This year's Canada Gairdner International Prize is shared by Rolf Kemler and Masatoshi Takeichi for the discovery of the cadherin family of Ca²⁺-dependent cell-cell adhesion proteins, which play essential roles in animal evolution, tissue development, and homeostasis, and are disrupted in human cancers.

Publication types

Biography
Historical Article

MeSH terms

Animals
Awards and Prizes
Biophysical Phenomena
Cadherins / metabolism*
Cadherins / physiology*
Canada
Cell Adhesion / physiology
Cell Communication / physiology*
History, 20th Century
History, 21st Century
Homeostasis / physiology
Humans
Male

Substances

Cadherins

Personal name as subject

Rolf Kemler
Masatoshi Takeichi