High-resolution computed tomography enhances the diagnosis and follow-up of influenza A (H1N1) virus-associated pneumonia

J Infect Dev Ctries. 2020 Mar 31;14(3):317-320. doi: 10.3855/jidc.11665.


Introduction: We present the findings on high-resolution computed tomography (HRCT) of influenza A (H1N1) virus-associated pneumonia of 140 patients with acute and post-acute pneumonia, totaling 189 exams in a retrospective observational study evaluating the importance of HRCT as a diagnostic imaging method in the acute phase and in the follow-up of pneumonia.

Methodology: We performed a retrospective observational study evaluating the HRCT findings of 140 adult patients with confirmed diagnosis of influenza A (H1N1) pneumonia and without other associated infectious processes. Chest X-ray exams were also performed in these patients.

Results: The main HRCT findings of lung involvement were airspace consolidation (57 cases), ground-glass opacities (40 cases) and an association of both aspects (43 cases), with a predominantly bilateral and peripheral distribution.

Conclusions: HRCT is able to distinguish small lesions, such as small areas of consolidation or ground glass opacities, with little increase in lung attenuation, when chest X-rays was normal, allowing a prompt diagnosis and treatment after imaging.

Keywords: H1N1; HRCT; Influenza A; air trapping; end expiration HRCT; pneumonia.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Influenza A Virus, H1N1 Subtype*
  • Influenza, Human / diagnostic imaging*
  • Male
  • Middle Aged
  • Pneumonia, Viral / diagnostic imaging*
  • Predictive Value of Tests
  • Retrospective Studies
  • Tomography, X-Ray Computed
  • Young Adult