Translocation of chlorantraniliprole and cyantraniliprole applied to corn as seed treatment and foliar spraying to control Spodoptera frugiperda (Lepidoptera: Noctuidae)

PLoS One. 2020 Apr 1;15(4):e0229151. doi: 10.1371/journal.pone.0229151. eCollection 2020.


The translocation of chemical insecticides in corn plants could enhance the control of Spodoptera frugiperda, based on their application form. Chlorantraniliprole and cyantraniliprole were applied via seed treatment and foliar spray in corn (VE and V3) to characterize the systemic action of both molecules in leaves that appeared after application. Bioassays with S. frugiperda and chemical quantification in LC-MS/MS confirmed the absorption and upward translocation of chlorantraniliprole and cyantraniliprole by xylem to new leaves. Both insecticides caused the mortality of larvae up to stage V6 (57.5±9.5% for chlorantraniliprole and 40±8.1% for cyantraniliprole), indicating the translocation of insecticides into leaves of corn plants when applied via seed treatment. However, the translocation of chlorantraniliprole and cyantraniliprole from sprayed leaves to new leaves was not observed, regardless of the stage of application plus the next first, second and third stages. An increased dosage of cyantraniliprole did not influence on its translocation in plant tissues, however, it influenced on the present amount of active ingredient. The application of chlorantraniliprole and cyantraniliprole in seed treatment is an important alternative for integrated pest management. The absorption and redistribution capacity of chlorantraniliprole and cyantraniliprole throughout the plant confer a prolonged residual action with satisfactory control of S. frugiperda.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Insect Control / methods*
  • Insecticides / toxicity*
  • Larva / drug effects
  • Plant Leaves
  • Pyrazoles / toxicity*
  • Seeds
  • Spodoptera / drug effects*
  • Zea mays*
  • ortho-Aminobenzoates / toxicity*


  • Insecticides
  • Pyrazoles
  • ortho-Aminobenzoates
  • chlorantranilipole
  • cyantraniliprole

Associated data

  • figshare/10.6084/m9.figshare.11894319

Grants and funding

This work was supported by the scholarship provided by CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior) to the first author, MP. The specific roles of this author is articulated in the author contributions section. FMC Agricultural Solutions also provided support for this study in the form of salaries for FMAS. Dupont and FMC Agricultural Solutions further supported this project with funding of research materials (technical and commercial products, pots for corn plants, corn seeds, and other research materials). The funder had no other role in study design, data collection and analysis, decision to publish, or preparation of the manuscript