Competence against insufficiency: Why are men mostly safe from a rare and deadly prostate cancer?

J Exp Med. 2020 Jun 1;217(6):e20200087. doi: 10.1084/jem.20200087.


Prostate cancer is a slow-growing disease, but not always. A highly rare and lethal form of the disease shows survival rates of less than a year. It is called squamous cell prostate carcinoma. In this issue of JEM, Hermanova et al. ( provide new findings in mouse demonstrating a strong genetic handle on both the reasons behind the rarity and the aggressiveness.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Animals
  • Carcinoma, Squamous Cell*
  • Humans
  • Male
  • Mice
  • Prostatic Neoplasms*