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. 2020 Jun:205:104789.
doi: 10.1016/j.bandl.2020.104789. Epub 2020 Mar 30.

Procedural and declarative memory brain systems in developmental language disorder (DLD)

Joanna C Lee  1 , Peggy C Nopoulos  2 , J Bruce Tomblin  1
Affiliations

Procedural and declarative memory brain systems in developmental language disorder (DLD)

Joanna C Lee et al. Brain Lang. 2020 Jun.

Abstract

The aim of the current study was to examine microstructural differences in white matter relevant to procedural and declarative memory between adolescents/young adults with and without Developmental Language Disorder (DLD) using diffusion tensor imaging (DTI). The findings showed atypical age-related changes in white matter structures in the corticostriatal system, in the corticocerebellar system, and in the medial temporal region in individuals with DLD. Results highlight the importance of considering the age factor in research on DLD. Future studies are needed to examine the developmental relationship between long-term memory and individual differences in language development and learning.

Keywords: Declarative memory brain system; Developmental language disorder; Diffusion tensor imaging; Procedural memory brain system.

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Figures

Figure 1.
Figure 1.
JHU white matter tractography atlas of regions of interest in the corticostriatal system. ALIC: Anterior limb of internal capsule; PLIC: Posterior limb of internal capsule; RLIC.
Figure 2.
Figure 2.
JHU white matter tractography atlas of regions of interest in the corticocerebellar system. CP: Cerebellar peduncle.
Figure 3.
Figure 3.
JHU white matter tractography atlas of regions of interest in the medial temporal region. CGC: Cingulum_cingulate gyrus; CGH: Cingulum_hippocampus.
Figure 4.
Figure 4.
Age-by-group interaction effect in the left anterior limb of the internal capsule (ALIC). FA: Fractional anisotropy.
Figure 5.
Figure 5.
Age-by-group interaction effect in the left superior cerebellar peduncle (SCP). FA: Fractional anisotropy.
Figure 6.
Figure 6.
Age-by-group interaction effect in the left fornix. FA: Fractional anisotropy.
See this image and copyright information in PMC

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References

    1. Adamaszek M, & Kirkby KC (2015). Cerebellum and grammar processing In Marien P & Manto M (Eds.), the linguistic cerebellum (pp.81–105). Cambridge, Massachusetts: Academic Press.
    1. Adams A, & Gathercole SE (2009). Limitations in working memory: Implications for language development. International Journal of Language and Communication Disorders, 35(1), 95–116. - PubMed
    1. Alexander AL, Lee JE, Lazar M, & Field AS (2007). Diffusion tensor imaging of the brain. Neurotherapeutics, 4, 316–329. - PMC - PubMed
    1. Alexander GE, DeLong MR, & Strick PL (1986). Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annual Review of Neuroscience, 9, 357–381. - PubMed
    1. Anthony JL, Davis C, Williams JM, & Anthony TI (2014). Preschoolers’ oral language ability: A multilevel examination of dimensionality. Learning and Individual Differences, 35, 56–61.

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