High-resolution computed tomography manifestations of COVID-19 infections in patients of different ages

Eur J Radiol. 2020 May;126:108972. doi: 10.1016/j.ejrad.2020.108972. Epub 2020 Mar 24.


Purpose: We aimed to compare chest HRCT lung signs identified in scans of differently aged patients with COVID-19 infections.

Methods: Case data of patients diagnosed with COVID-19 infection in Hangzhou City, Zhejiang Province in China were collected, and chest HRCT signs of infected patients in four age groups (<18 years, 18-44 years, 45-59 years, ≥60 years) were compared.

Results: Small patchy, ground-glass opacity (GGO), and consolidations were the main HRCT signs in 98 patients with confirmed COVID-19 infections. Patients aged 45-59 years and aged ≥60 years had more bilateral lung, lung lobe, and lung field involvement, and greater lesion numbers than patients <18 years. GGO accompanied with the interlobular septa thickening or a crazy-paving pattern, consolidation, and air bronchogram sign were more common in patients aged 45-59 years, and ≥60 years, than in those aged <18 years, and aged 18-44 years.

Conclusions: Chest HRCT manifestations in patients with COVID-19 are related to patient's age, and HRCT signs may be milder in younger patients.

Keywords: COVID-19; Ground-glass opacity; High-resolution computed tomography; Pure ground-glass opacity.

MeSH terms

  • Adolescent
  • Adult
  • Betacoronavirus*
  • COVID-19
  • China
  • Coronavirus Infections / diagnostic imaging*
  • Female
  • Humans
  • Lung / diagnostic imaging
  • Male
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / diagnostic imaging*
  • SARS-CoV-2
  • Thorax / diagnostic imaging
  • Tomography, X-Ray Computed / methods
  • Young Adult