Hydrophilic polyphosphazenes as hydrogels: radiation cross-linking and hydrogel characteristics of poly[bis(methoxyethoxyethoxy)phosphazene]

Biomaterials. 1988 Nov;9(6):509-13. doi: 10.1016/0142-9612(88)90046-4.

Abstract

The water-soluble polyphosphazene, [NP(OCH2CH2OCH2CH2OCH3)2]n, cross-links when exposed to gamma rays to form hydrophilic, water-swellable membranes and hydrogels. The degree of cross-linking increases with irradiation dose in a manner that can be utilized to change the properties. gamma irradiation studies of the small molecule model compound, [NP(OCH2CH2OCH2CH2OCH3)2]4, were also carried out to probe the relationship between irradiation dose and cross-link density.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chemical Phenomena
  • Chemistry, Physical
  • Delayed-Action Preparations
  • Diffusion
  • Gels
  • Hydrogen-Ion Concentration
  • Membranes, Artificial
  • Molecular Structure
  • Organophosphorus Compounds* / chemical synthesis
  • Organophosphorus Compounds* / radiation effects
  • Polymers* / chemical synthesis
  • Polymers* / radiation effects
  • Solubility

Substances

  • Delayed-Action Preparations
  • Gels
  • Membranes, Artificial
  • Organophosphorus Compounds
  • Polymers
  • poly(bis(methoxyethoxyethoxy)phosphazene)