Diagnosis and hormonal treatment of male infertility

Actas Urol Esp (Engl Ed). 2020 Jun;44(5):321-327. doi: 10.1016/j.acuro.2019.10.013. Epub 2020 Mar 30.
[Article in English, Spanish]


Male infertility is a frequently observed medical condition that is related to the functioning of extremely complex organs such as the pituitary gland and the gonads. The diagnosis and proper management of infertile men is challenging for modern medicine, given the high expectations and demands of current patients, mainly due to the economic and emotional expenses aroused by this "relationship issue". In many cases, patients should receive therapies aimed at improving the functioning of that complex hormonal axis, instead of treating their underlying problem; thus, seeking to optimize the production of gametes with better conditions and improve fertilization rates without requiring assisted procedures.

Keywords: Azoospermia; Azzoospermia; Eje hipotálamo-hipófisis-gónada; Espermograma; Hypothalamic-pituitary-gonadal axis; Spermiogram.

Publication types

  • Review

MeSH terms

  • Hormones / therapeutic use
  • Humans
  • Infertility, Male / diagnosis*
  • Infertility, Male / drug therapy*
  • Male


  • Hormones