A Group of Complexes Based on PAMAM and Quantum Dots Used in Clinical Immunoassays

Nanoscale Res Lett. 2020 Apr 3;15(1):71. doi: 10.1186/s11671-020-3291-5.


We report a group of complexes used in clinical immunoassays. The complexes include a PAMAM-conjugated goat anti-rabbit IgG and a QDs-conjugated goat anti-mouse IgG. When rabbit anti-antigen and mouse anti-antigen are added, the corresponding antigen will be detected. The experiment, using the complexes, is simple, convenient, short in time, and short in steps. It is also applicable to different experiment methods, like to be used with FCM (flow cytometry), ICC (immunocytochemistry), and IHC (immunohistochemistry) to detect many kinds of antigens.

Keywords: Clinical immunoassays; FCM; PAMAM; Quantum dots.