The potential health benefits of the isoflavone glycoside genistin

Arch Pharm Res. 2020 Apr;43(4):395-408. doi: 10.1007/s12272-020-01233-2. Epub 2020 Apr 7.

Abstract

Genistin is a type of isoflavone glycoside and has a broad range of health benefits. It is found in a variety of dietary plants, such as soybean, kudzu (Japanese arrowroot), and other plant-based products. Genistin has been described to have several beneficial health impacts, such as decreasing the risk of osteoporosis and post-menopausal symptoms, as well as anti-cancer, anti-oxidative, cardioprotective, anti-apoptotic, neuroprotective, hepatoprotective, and anti-microbial activities. It may also assist individuals with metabolic syndrome. This review summarizes some of the molecular impacts and prospective roles of genistin in maintaining and treatment of health disorders. The review could help to develop novel genistin medicine with significant health benefits for application in the nutraceutical and pharmaceutical fields.

Keywords: Genistin; Health disorders; Isoflavone; Therapeutic activity.

Publication types

  • Review

MeSH terms

  • Humans
  • Insurance Benefits*
  • Isoflavones / pharmacology*

Substances

  • Isoflavones
  • genistin