Angiotensin converting enzyme 2 (ACE2) is the major enzyme responsible for conversion of Ang II into Ang-(1-7). It also acts as the receptor for severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2, which causes Coronavirus Disease (COVID)-19. In recognition of the importance of ACE2 and to celebrate 20 years since its discovery, the journal will publish a focused issue on the basic science and (patho)physiological role of this multifunctional protein.
Keywords: ACE2 receptor; Angiotensin; COVID-19; cardiovascular; coronavirus; hypertension.
© 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.