Semi supervised data mining model for the prognosis of pre-diabetic conditions in type 2 Diabetes Mellitus

Bioinformation. 2019 Dec 31;15(12):875-882. doi: 10.6026/97320630015875. eCollection 2019.

Abstract

Diabetic Mellitus is the leading disease in the world irrespective of age and geographical location. It is estimated that 43% of the overall population is affected by the disease. The reasons for the disease include inappropriate diet lifestyle with allied symptoms like obesity. Therefore, the prognosis and diagnosis of the disease are important for adequate combat and care. The prognosis related known symptoms of the disease include incontinence (inability to control urination) and frequent fatigue. Moreover, early prediction of the disease plays an important role in the prognosis of other associated conditions such as heart failure leading to chronic illness. Hence, it is of interest to describe a data mining based prediction model using known features (derived from epidemiological data collected from the public hospital using routine tests) to help in the prognosis of the disease. We used data pre-processing techniques for handling missing values and dimensionality reduction models to improve data quality. The Minimum Description Length principle (MDL) model for discretization (replacing a continuum with a finite set of points) is used to reduce high-level dimensionality of the dataset, which enabled to categorize the dataset into small groups in ordered intervals. Thus, we describe a semi-supervised learning technique (identifies promising attributes using clustering and classification methods) by combining data mining techniques for reasonable accuracy having adequate sensitivity and specificity for further discussion, cross-validation, revaluation, and application. Early prediction of the disease with improved accuracy by analysing specificity ranges in blood pressure and glucose levels will be useful to combat Diabetes Mellitus.

Keywords: Diabetes; classification; clustering; epidemiological data; prognosis; semi supervised learning.