Meta-Analysis of Mid- p-Values: Some New Results based on the Convex Order

J Am Stat Assoc. 2018 Aug 6;114(527):1105-1112. doi: 10.1080/01621459.2018.1469994. eCollection 2019.

Abstract

The mid-p-value is a proposed improvement on the ordinary p-value for the case where the test statistic is partially or completely discrete. In this case, the ordinary p-value is conservative, meaning that its null distribution is larger than a uniform distribution on the unit interval, in the usual stochastic order. The mid-p-value is not conservative. However, its null distribution is dominated by the uniform distribution in a different stochastic order, called the convex order. The property leads us to discover some new finite-sample and asymptotic bounds on functions of mid-p-values, which can be used to combine results from different hypothesis tests conservatively, yet more powerfully, using mid-p-values rather than p-values. Our methodology is demonstrated on real data from a cyber-security application.

Keywords: Convex order; Cyber-security; Meta-analysis; Network; p-Value.

Grants and funding

DJL was funded under a Sir Henry Dale Wellcome Trust Fellowship number WT104125MA.