Meiosis: Location, Location, Location, How Crossovers Ensure Segregation

Stacie E Hughes; R Scott Hawley

doi:10.1016/j.cub.2020.02.020

Meiosis: Location, Location, Location, How Crossovers Ensure Segregation

Curr Biol. 2020 Apr 6;30(7):R311-R313. doi: 10.1016/j.cub.2020.02.020.

Authors

Stacie E Hughes¹, R Scott Hawley²

Affiliations

¹ Stowers Institute for Medical Research, 1000 E. 50(th) St., Kansas City, MO 64110, USA.
² Stowers Institute for Medical Research, 1000 E. 50(th) St., Kansas City, MO 64110, USA; Department of Molecular and Integrative Physiology, University of Kansas Medical Center, 3901 Rainbow Blvd., Kansas City, KS 66160, USA. Electronic address: rsh@stowers.org.

PMID: 32259504
DOI: 10.1016/j.cub.2020.02.020

Abstract

The proper behavior of homologous chromosomes at the first meiotic division is usually ensured by crossing over. A new study shows that crossover position influences the successful completion of the chromatin remodeling processes that facilitate homologous segregation.

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MeSH terms

Chromosome Segregation*
Chromosomes / genetics
Crossing Over, Genetic*
Meiosis