Syphilitic chorioretinitis presenting as a choroidal granuloma

BMJ Case Rep. 2020 Apr 6;13(4):e234022. doi: 10.1136/bcr-2019-234022.

Abstract

A rare case of syphilitic uveitis presenting as a choroidal granuloma is described in this case report. The clinical picture resembled that of a tubercular choroidal granuloma. However, the patient was positive for treponemal (treponema pallidum hemagglutination assay) as well as non-treponemal tests (venereal disease research laboratory test) for syphilis. Therefore, the patient was treated for ocular syphilis and responded to antisyphilitic therapy. There was a complete resolution of the lesion at the end of 14 days of treatment.

Keywords: infectious diseases; retina; syphilis.

Publication types

  • Case Reports

MeSH terms

  • Administration, Intravenous
  • Adult
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Chorioretinitis / microbiology*
  • Choroid / pathology*
  • Diagnosis, Differential
  • Eye Infections, Bacterial / microbiology*
  • Fundus Oculi
  • Granuloma / diagnosis*
  • Granuloma / microbiology
  • Hemagglutination Tests / methods
  • Humans
  • Male
  • Penicillin G / administration & dosage
  • Penicillin G / therapeutic use
  • Syphilis / complications
  • Syphilis / diagnosis*
  • Syphilis / drug therapy
  • Tomography, Optical Coherence / methods
  • Treatment Outcome
  • Treponema pallidum / isolation & purification

Substances

  • Anti-Bacterial Agents
  • Penicillin G