The role of the vitreous in diabetic macular edema

Ophthalmology. 1988 Oct;95(10):1335-9. doi: 10.1016/s0161-6420(88)33004-6.


The authors assessed retrospectively clinical records of 76 patients (125 eyes) 60 years of age or older with diabetic retinopathy who had undergone a vitreous examination. The groups consisted of 105 eyes (63 patients) with macular edema and 20 eyes (13 patients) without macular edema. Vitreous studies were done using the El Bayadi-Kajiura lens to determine whether or not the posterior vitreous was attached to the retina in the macula. Twenty-one of 105 eyes (20.0%) in the edema group and 11 of 20 eyes (55.0%) in the no-edema group had a detached posterior vitreous. This difference was found to be statistically significant, indicating that diabetic cases without macular edema have a significantly higher rate of posterior vitreous detachment than those with macular edema. This study demonstrates that the vitreous may play a role in diabetic macular edema.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Diabetic Retinopathy / complications
  • Diabetic Retinopathy / pathology*
  • Edema / complications
  • Edema / pathology*
  • Female
  • Fluorescein Angiography
  • Humans
  • Macula Lutea / pathology*
  • Male
  • Middle Aged
  • Retinal Detachment / complications
  • Retinal Detachment / diagnosis
  • Retrospective Studies
  • Vitreous Body / pathology*