Agreement between equations-estimated resting metabolic rate and indirect calorimetry-estimated resting metabolic rate in low-income obese women

Arch Endocrinol Metab. 2020 Aug;64(4):402-411. doi: 10.20945/2359-3997000000226. Epub 2020 Apr 6.

Abstract

Objectives Indirect calorimetry is established as a gold standard to determine the resting metabolic rate (RMR), however, its clinical use is limited, especially in low-income settings. Thus, the use of predictive equations appear as an alternative to estimate the RMR, but its precision is debatable, especially in obese individuals and in populations without specifically developed equations. To evaluate the agreement between the RMR estimated by equations and by indirect calorimetry in low-income obese women. Subjects and methods A cross-sectional study with adult and obese women, which estimated the RMR by indirect calorimetry and compared with 13 predictive equations using the concordance correlation coefficient, root mean square error (RMSE) and Bland-Altman methods. The maximum allowed differences were predefined as 10%. Results No equation presented its confidence intervals for the Bland-Altman limits of agreement inside the predefined acceptable range. The Harris-Benedict equation achieved better agreement (bias of 2.9% and RMSE of 274.3kcal) whereas the Henry-Rees equation achieved better precision (42.3% of the sample within the 10% maximum allowed difference). Conclusion None of the studied equations satisfactorily estimated the RMR estimated by indirect calorimetry. In the absence of specific equations for this population, the use of the Harris-Benedict and Henry-Rees equations could be considered.

MeSH terms

  • Adult
  • Basal Metabolism*
  • Calorimetry, Indirect
  • Cross-Sectional Studies
  • Energy Metabolism
  • Female
  • Humans
  • Obesity*

Grants and funding

Funding sources: this work was partially funded by Fundação de Amparo à Pesquisa do Estado de Alagoas (FAPEAL) [number 14/2016] and by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) with a research grant for Pureza IR [under the number of process 1793050].