New Microglia on the Block

Cell Metab. 2020 Apr 7;31(4):664-666. doi: 10.1016/j.cmet.2020.03.015.

Abstract

Microglia exhibit differing functions and phenotypes depending on life stage and the context of health or disease. Recently, in Nature Neuroscience, Marschallinger et al. (2020) described a new state of microglia, namely "lipid-droplet-accumulating microglia" (LDAM), that contributes to neuronal inflammation and age-related neurodegeneration.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Aging
  • Brain*
  • Humans
  • Inflammation
  • Lipids
  • Microglia*

Substances

  • Lipids