A model reaction for the repair of nucleic acids. The repair of thymidine bromohydrins

Nucleic Acids Symp Ser. 1988:(19):107-10.

Abstract

Bromohydrins, which were damaged products of thymidines (2, 3, and 4), were repaired with sunlight of heat via a radical mechanism to regenerate the thymidines. A hypothesis for the biological significance of thymidine in DNA is presented.

MeSH terms

  • DNA Damage*
  • DNA Repair*
  • Hot Temperature
  • Models, Genetic
  • Molecular Structure
  • Structure-Activity Relationship
  • Sunlight
  • Thymidine / analogs & derivatives*

Substances

  • thymidine bromohydrin
  • Thymidine