Co-morbidities in a Retrospective Cohort of Prostate Cancer Patients

Ethn Dis. 2020 Apr 2;30(Suppl 1):185-192. doi: 10.18865/ed.30.S1.185. eCollection 2020.

Abstract

Objective: To characterize rates of co-morbidity among prostate cancer patients treated with radical prostatectomy and to examine the association between co-morbidity status and race, clinical factors, and health behaviors for cancer control.

Design/study participants: Retrospective cohort study among prostate cancer patients treated with radical prostatectomy.

Setting: Academic medical center located in the southeastern region of the United States.

Main outcome measure: Patients with at least one of five co-morbid conditions considered were categorized as having a co-morbidity, and those without any were categorized as not having a co-morbid condition. Co-morbid conditions considered were hypertension, diabetes, heart problems, stroke, and high cholesterol, which had been recorded in the electronic medical record as part of their past medical history.

Results: Fifty-one percent of participants had a co-morbidity, with hypertension being the most common. The average number of co-morbidities among study participants was .87. In a multivariate logistic regression analysis, being diagnosed with prostate cancer within the past four years was associated with an increased likelihood of having a co-morbidity (OR=4.71, 95% CI=2.69, 8.25, P=.0001) compared with diagnosis five or more years ago. Age was also associated with an increased likelihood of having a co-morbidity (OR=1.30, 95% CI=1.005, 1.68, P=.05). In this study cohort, race, stage at diagnosis, and PSA level were not statistically associated with co-morbidity status.

Conclusion: Better chronic disease management is needed among prostate cancer survivors through more effective survivorship care planning and interventions that promote health behaviors.

Keywords: Co-morbidities; Prostate Cancer; Retrospective Cohort.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Cohort Studies
  • Comorbidity
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Prevalence
  • Prostatectomy
  • Prostatic Neoplasms / epidemiology*
  • Prostatic Neoplasms / therapy*
  • Retrospective Studies
  • Risk Factors
  • United States