ILROG emergency guidelines for radiation therapy of hematological malignancies during the COVID-19 pandemic

Blood. 2020 May 21;135(21):1829-1832. doi: 10.1182/blood.2020006028.


The International Lymphoma Radiation Oncology Group (ILROG) guidelines for using radiation therapy (RT) in hematological malignancies are widely used in many countries. The emergency situation created by the COVID-19 pandemic may result in limitations of treatment resources. Furthermore, in recognition of the need to also reduce the exposure of patients and staff to potential infection with COVID-19, the ILROG task force has made recommendations for alternative radiation treatment schemes. The emphasis is on maintaining clinical efficacy and safety by increasing the dose per fraction while reducing the number of daily treatments. The guidance is informed by adhering to acceptable radiobiological parameters and clinical tolerability. The options for delaying or omitting RT in some hematological categories are also discussed.

Publication types

  • Practice Guideline

MeSH terms

  • Betacoronavirus / isolation & purification
  • COVID-19
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / prevention & control
  • Hematologic Neoplasms / radiotherapy*
  • Humans
  • Lymphoma / radiotherapy*
  • Pandemics / prevention & control
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / prevention & control
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted
  • Risk Factors
  • SARS-CoV-2
  • Time Factors