Use of Convalescent Plasma Therapy in Two COVID-19 Patients With Acute Respiratory Distress Syndrome in Korea

J Korean Med Sci. 2020 Apr 13;35(14):e149. doi: 10.3346/jkms.2020.35.e149.


Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 not yet has established its treatment, but convalescent plasma has been expected to increase survival rates as in the case with other emerging viral infections. We describe two cases of COVID-19 treated with convalescent plasma infusion. Both patients presented severe pneumonia with acute respiratory distress syndrome and showed a favorable outcome after the use of convalescent plasma in addition to systemic corticosteroid. To our knowledge, this is the first report of the use of convalescent plasma therapy for COVID-19 in Korea.

Keywords: COVID-19; Convalescent Plasma; Coronavirus; SARS-CoV-2; Treatment.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Betacoronavirus*
  • Coronavirus Infections / therapy*
  • Female
  • Humans
  • Immunization, Passive
  • Male
  • Pandemics
  • Pneumonia, Viral / therapy*
  • Republic of Korea
  • Respiratory Distress Syndrome, Adult / therapy

Supplementary concepts

  • COVID-19
  • COVID-19 serotherapy
  • severe acute respiratory syndrome coronavirus 2