Esophagogastric Junction Opening Parameters Are Consistently Abnormal in Untreated Achalasia

Clin Gastroenterol Hepatol. 2021 May;19(5):1058-1060.e1. doi: 10.1016/j.cgh.2020.03.069. Epub 2020 Apr 11.

Abstract

Achalasia is a disorder of impaired lower esophageal sphincter (LES) relaxation and failed peristalsis traditionally characterized by manometry.1 As impaired LES relaxation is a mechanism of reduced esophagogastric junction (EGJ) opening, abnormally reduced EGJ distensibility assessed with functional luminal imaging probe (FLIP) was reported among patients with untreated achalasia.2-5 Therefore, we aimed to describe the performance characteristics of EGJ opening parameters on FLIP panometry among a large cohort of treatment-naïve achalasia patients.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Esophageal Achalasia* / diagnostic imaging
  • Esophageal Sphincter, Lower
  • Esophagogastric Junction / diagnostic imaging
  • Humans
  • Manometry
  • Peristalsis