The Role of Nutrition in Attenuating Age-Related Skeletal Muscle Atrophy

Adv Exp Med Biol. 2020:1260:297-318. doi: 10.1007/978-3-030-42667-5_12.


The elderly population is increasing rapidly worldwide, and we are faced with the significant challenge for maintaining or improving physical activity, independence, and quality of life. Sarcopenia, the age-related decline of skeletal muscle mass, is characterized by loss of muscle quantity and quality resulting to a gradual slowing of movement, a decrease in strength and power, elevated risk of fall-related injury, and often frailty. Supplemental, hormonal, and pharmacological approaches have been attempted to attenuate sarcopenia but these have not achieved outstanding results. In this review, we summarize the current knowledge of nutrition-based therapies for counteracting sarcopenia.

Keywords: Aging; Diet; Exercise; Muscle atrophy; Nutrition; Sarcopenia.

Publication types

  • Review

MeSH terms

  • Aged
  • Aging / pathology*
  • Humans
  • Muscle Strength
  • Muscle, Skeletal / pathology*
  • Nutritional Status*
  • Quality of Life
  • Sarcopenia / diet therapy*
  • Sarcopenia / pathology*
  • Sarcopenia / prevention & control