The value of calcium dobesilate in the treatment of diabetic retinopathy. A controlled clinical trial

Diabetologia. 1977 Apr;13(2):105-9. doi: 10.1007/BF00745136.


The effect of calcium dobesilate on capillary resistance and background retinopathy was compared with placebo in a double-blind cross-over trial on 18 diabetics. Each treatment lasted 8 months. The trial produced no evidence in favour of a significant beneficial effect of calcium dobesilate on the capillary resistance in diabetics or on the course of the diabetic retinopathy.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Benzenesulfonates / therapeutic use*
  • Calcium Dobesilate / therapeutic use*
  • Capillary Resistance / drug effects
  • Clinical Trials as Topic
  • Diabetic Retinopathy / diagnostic imaging
  • Diabetic Retinopathy / drug therapy*
  • Female
  • Fluorescein Angiography
  • Humans
  • Male
  • Middle Aged
  • Radiography


  • Benzenesulfonates
  • Calcium Dobesilate