Silver sulfadiazine is a medication used to prevent, manage, and treat burn wound infections. It is a heavy metal topical agent with antibacterial properties. This activity reviews the indications, action, and contraindications for silver sulfadiazine as a valuable agent in preventing infection in burn patients. This activity will highlight the mechanism of action, adverse event profile, and other key factors (eg, off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for members of the healthcare team in the care of patients with second and third-degree burns.
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