Cardiac Manifestations of Coronavirus (COVID-19)

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.


Coronaviruses are a large family of single-stranded positive-sense, enveloped RNA viruses that can infect many animal species. Human coronaviruses can be divided based on their pathogenicity. The types with high pathogenicity include SARS-CoV, MERS-CoV, and the current novel SARS-CoV2 viruses.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections were first identified in December 2019 and termed coronavirus disease 2019 (COVID-19). By March 2020, it was declared a global pandemic by the World Health Organization (WHO).

Although primarily a respiratory disease, COVID-19 has been associated with many cardiac complications. Cardiac injury is recognized as one of the most frequent complications of the disease. Long-term cardiac complications following COVID-19 include ischemic heart disease, heart failure, arrhythmias, and myocarditis.

Studies have consistently shown that underlying cardiovascular disease in patients with COVID-19 and/or the development of acute cardiac injury due to COVID-19 illness is associated with significantly worse outcomes. This activity reviews the clinical manifestations of cardiac complications related to COVID-19 infections and outlines their recommended evaluation as well as their treatment.

Publication types

  • Study Guide