Sudden hearing loss in an adolescent following a single dose of cisplatin

ORL J Otorhinolaryngol Relat Spec. 1988;50(6):405-8. doi: 10.1159/000276021.


Progressive hearing loss after cisplatin therapy is relatively frequent, specially in older patients, but it is less common in children and in acute form. The case of a 17-year-old patient with an intracranial tumor who suffered sudden deafness after a single course of cisplatin is presented. This patient had a previously documented very good hearing up to 20 kHz. Although it has been suggested that children with irradiated brain tumors may have an increased susceptibility to cisplatin-induced hearing loss, in this case the patient had not been subjected to radiotherapy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Brain Neoplasms / drug therapy*
  • Cisplatin / adverse effects*
  • Cisplatin / therapeutic use
  • Dysgerminoma / drug therapy*
  • Hearing Loss, Sudden / chemically induced*
  • Humans
  • Male


  • Cisplatin