When the Community Silences Disruptive Elements: Multiscale Mechanical Coupling Buffers Morphogenetic Imprecisions

Dev Cell. 2020 Apr 20;53(2):135-137. doi: 10.1016/j.devcel.2020.03.024.


How the high degree of shape reproducibility is conferred between individuals remains unclear. In this issue of Developmental Cell, Eritano et al. show that tissue-scale mechanical coupling corrects the intrinsic noise of gene expression pattern and tissue mechanics to ensure the high degree of precision of Drosophila cephalic furrow formation.

Publication types

  • Comment

MeSH terms

  • Animals
  • Buffers
  • Drosophila Proteins* / genetics
  • Elements
  • Humans
  • Reproducibility of Results
  • Residence Characteristics
  • Weights and Measures


  • Buffers
  • Drosophila Proteins
  • Elements