Detection of the United States Neisseria meningitidis urethritis clade in the United Kingdom, August and December 2019 - emergence of multiple antibiotic resistance calls for vigilance

Euro Surveill. 2020 Apr;25(15):2000375. doi: 10.2807/1560-7917.ES.2020.25.15.2000375.

Abstract

Since 2015 in the United States (US), the US Neisseria meningitidis urethritis clade (US_NmUC) has caused a large multistate outbreak of urethritis among heterosexual males. Its 'parent' strain caused numerous outbreaks of invasive meningococcal disease among men who have sex with men in Europe and North America. We highlight the arrival and dissemination of US_NmUC in the United Kingdom and the emergence of multiple antibiotic resistance. Surveillance systems should be developed that include anogenital meningococci.

Keywords: Heterosexual; Invasive meningococcal disease; MSM; Meningococcal; Urethritis; antibiotic resistance.

MeSH terms

  • Adult
  • Disease Outbreaks
  • Drug Resistance, Microbial
  • Female
  • Humans
  • Male
  • Neisseria meningitidis / classification
  • Neisseria meningitidis / isolation & purification*
  • Phylogeny
  • Polymorphism, Single Nucleotide
  • United Kingdom / epidemiology
  • United States
  • Urethritis / diagnosis*
  • Urethritis / drug therapy
  • Urethritis / epidemiology