Primary low-grade mucinous adenocarcinoma spleen resulting in Pseudomyxoma peritonei: A case report

Indian J Pathol Microbiol. 2020 Apr-Jun;63(2):286-288. doi: 10.4103/IJPM.IJPM_624_19.


A 61-year-old man presented with complaints of abdominal pain, loss of weight, and splenomegaly since past 6 months. On computed tomography, the spleen was totally replaced by multiloculated cysts and splenectomy was performed. Pathological examination revealed a low-grade mucinous adenocarcinoma. Postoperative PET scan was negative, and in the absence of a primary tumor elsewhere, we considered this tumor to be primary in the spleen, and it was presumed that the tumor arose from invaginated capsular mesothelium of the spleen.

Keywords: Mucinous adenocarcinoma; pseudomyxoma peritonei; spleen.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma, Mucinous / complications*
  • Adenocarcinoma, Mucinous / diagnosis*
  • Humans
  • Male
  • Middle Aged
  • Peritoneal Neoplasms / diagnosis
  • Pseudomyxoma Peritonei / diagnostic imaging*
  • Pseudomyxoma Peritonei / etiology*
  • Spleen / diagnostic imaging*
  • Spleen / pathology*
  • Spleen / surgery
  • Splenectomy
  • Tomography, X-Ray Computed