Albuminuria-lowering effect of sodium-glucose cotransporter 2 inhibitors could be partly attributable to the attenuation of tubular damage in type 2 diabetic patients

Diabetes Metab Res Rev. 2020 Oct;36(7):e3327. doi: 10.1002/dmrr.3327. Epub 2020 Jun 10.

Authors

Katsuyuki Yanagisawa¹, Ami Sotokawauchi², Yuri Nishino², Takanori Matsui², Nobuhiro Tahara³, Sho-Ichi Yamagishi⁴

Affiliations

¹ Souen Diabetes Clinic, Sapporo, Japan.
² Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University School of Medicine, Kurume, Japan.
³ Department of Medicine, Kurume University School of Medicine, Kurume, Japan.
⁴ Division of Diabetes, Metabolism and Endocrinology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.

PMID: 32319149
DOI: 10.1002/dmrr.3327

No abstract available

Keywords: SGLT2; advanced glycation end products; albuminuria; diabetic nephropathy; tubular damage.