Asymptomatic Transmission, the Achilles' Heel of Current Strategies to Control Covid-19

doi:10.1056/NEJMe2009758

Editorial

. 2020 May 28;382(22):2158-2160.

doi: 10.1056/NEJMe2009758. Epub 2020 Apr 24.

Asymptomatic Transmission, the Achilles' Heel of Current Strategies to Control Covid-19

Monica Gandhi¹, Deborah S Yokoe¹, Diane V Havlir¹

Affiliations

PMID: 32329972
PMCID: PMC7200054
DOI: 10.1056/NEJMe2009758

Editorial

Asymptomatic Transmission, the Achilles' Heel of Current Strategies to Control Covid-19

Monica Gandhi et al. N Engl J Med. 2020.

. 2020 May 28;382(22):2158-2160.

doi: 10.1056/NEJMe2009758. Epub 2020 Apr 24.

Authors

Monica Gandhi¹, Deborah S Yokoe¹, Diane V Havlir¹

Affiliation

¹ From the Department of Medicine, University of California, San Francisco.

PMID: 32329972
PMCID: PMC7200054
DOI: 10.1056/NEJMe2009758

No abstract available

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Comment in

Screening for Covid-19 in Skilled Nursing Facilities.
Krsak M, Henao-Martínez AF, Franco-Paredes C. Krsak M, et al. N Engl J Med. 2020 Jul 9;383(2):190-191. doi: 10.1056/NEJMc2017362. Epub 2020 May 29. N Engl J Med. 2020. PMID: 32469480 No abstract available.
Screening for Covid-19 in Skilled Nursing Facilities.
Calbo E, Masats Ú, Garau J. Calbo E, et al. N Engl J Med. 2020 Jul 9;383(2):191. doi: 10.1056/NEJMc2017362. Epub 2020 May 29. N Engl J Med. 2020. PMID: 32469481 No abstract available.
Screening for Covid-19 in Skilled Nursing Facilities.
Huber DH. Huber DH. N Engl J Med. 2020 Jul 9;383(2):191-192. doi: 10.1056/NEJMc2017362. Epub 2020 May 29. N Engl J Med. 2020. PMID: 32469482 No abstract available.
Individuals with covert severe acute respiratory syndrome coronavirus 2 infection: Are they a critical booby-trap?
Amer FA. Amer FA. Rev Soc Bras Med Trop. 2020;53:e20200231. doi: 10.1590/0037-8682-0231-2020. Epub 2020 Jun 1. Rev Soc Bras Med Trop. 2020. PMID: 32491107 Free PMC article. No abstract available.

Comment on

Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility.
Arons MM, Hatfield KM, Reddy SC, Kimball A, James A, Jacobs JR, Taylor J, Spicer K, Bardossy AC, Oakley LP, Tanwar S, Dyal JW, Harney J, Chisty Z, Bell JM, Methner M, Paul P, Carlson CM, McLaughlin HP, Thornburg N, Tong S, Tamin A, Tao Y, Uehara A, Harcourt J, Clark S, Brostrom-Smith C, Page LC, Kay M, Lewis J, Montgomery P, Stone ND, Clark TA, Honein MA, Duchin JS, Jernigan JA; Public Health–Seattle and King County and CDC COVID-19 Investigation Team. Arons MM, et al. N Engl J Med. 2020 May 28;382(22):2081-2090. doi: 10.1056/NEJMoa2008457. Epub 2020 Apr 24. N Engl J Med. 2020. PMID: 32329971 Free PMC article.

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Archambault PM, Rosychuk RJ, Audet M, Hau JP, Graves L, Décary S, Perry JJ, Brooks SC, Morrison LJ, Daoust R, Yeom DS, Wiemer H, Fok PT, McRae AD, Chandra K, Kho ME, Stacey D, Vissandjée B, Menear M, Mercier E, Vaillancourt S, Aziz S, Zakaria D, Davis P, Dainty KN, Paquette JS, Leeies M, Goulding S, Berger Pelletier E, Hohl CM; Canadian COVID−19 Emergency Department Rapid Response Network (CCEDRRN) investigators; Network of Canadian Emergency Researchers; Canadian Critical Care Trials Group investigators. Archambault PM, et al. Nat Commun. 2024 Sep 30;15(1):8449. doi: 10.1038/s41467-024-52404-4. Nat Commun. 2024. PMID: 39349926 Free PMC article.
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References

1. Wölfel R, Corman VM, Guggemos W, et al. Virological assessment of hospitalized patients with COVID-2019. Nature 2020. April 1 (Epub ahead of print). - PubMed
1. Cheng PK, Wong DA, Tong LK, et al. Viral shedding patterns of coronavirus in patients with probable severe acute respiratory syndrome. Lancet 2004;363:1699-1700. - PMC - PubMed
1. To KK-W, Tsang OT-Y, Leung W-S, et al. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis 2020. March 23 (Epub ahead of print). - PMC - PubMed
1. Ip DKM, Lau LLH, Leung NHL, et al. Viral shedding and transmission potential of asymptomatic and paucisymptomatic influenza virus infections in the community. Clin Infect Dis 2017;64:736-742. - PMC - PubMed
1. Arons MM, Hatfield KM, Reddy SC, et al. Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility. N Engl J Med. DOI: 10.1056/NEJMoa2008457. - DOI - PMC - PubMed

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[1] Wölfel R, Corman VM, Guggemos W, et al. Virological assessment of hospitalized patients with COVID-2019. Nature 2020. April 1 (Epub ahead of print). - PubMed

[2] Wölfel R, Corman VM, Guggemos W, et al. Virological assessment of hospitalized patients with COVID-2019. Nature 2020. April 1 (Epub ahead of print). - PubMed

[3] Cheng PK, Wong DA, Tong LK, et al. Viral shedding patterns of coronavirus in patients with probable severe acute respiratory syndrome. Lancet 2004;363:1699-1700. - PMC - PubMed

[4] Cheng PK, Wong DA, Tong LK, et al. Viral shedding patterns of coronavirus in patients with probable severe acute respiratory syndrome. Lancet 2004;363:1699-1700. - PMC - PubMed

[5] To KK-W, Tsang OT-Y, Leung W-S, et al. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis 2020. March 23 (Epub ahead of print). - PMC - PubMed

[6] To KK-W, Tsang OT-Y, Leung W-S, et al. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis 2020. March 23 (Epub ahead of print). - PMC - PubMed

[7] Ip DKM, Lau LLH, Leung NHL, et al. Viral shedding and transmission potential of asymptomatic and paucisymptomatic influenza virus infections in the community. Clin Infect Dis 2017;64:736-742. - PMC - PubMed

[8] Ip DKM, Lau LLH, Leung NHL, et al. Viral shedding and transmission potential of asymptomatic and paucisymptomatic influenza virus infections in the community. Clin Infect Dis 2017;64:736-742. - PMC - PubMed

[9] Arons MM, Hatfield KM, Reddy SC, et al. Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility. N Engl J Med. DOI: 10.1056/NEJMoa2008457. - DOI - PMC - PubMed

[10] Arons MM, Hatfield KM, Reddy SC, et al. Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility. N Engl J Med. DOI: 10.1056/NEJMoa2008457. - DOI - PMC - PubMed

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Asymptomatic Transmission, the Achilles' Heel of Current Strategies to Control Covid-19

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Asymptomatic Transmission, the Achilles' Heel of Current Strategies to Control Covid-19

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