Head and neck surgical antibiotic prophylaxis in resource-constrained settings

Curr Opin Otolaryngol Head Neck Surg. 2020 Jun;28(3):188-193. doi: 10.1097/MOO.0000000000000626.


Purpose of review: Antimicrobial resistance represents a global threat and causes almost 700 000 deaths per year. The rapid dissemination of resistant bacteria is occurring globally, turning this into the primary threat to public health in the 21st century and forcing organizations around the globe to take urgent action.

Recent findings: About risks related to surgical site infection (SSI) in head and neck surgery, surgical limitations in resource-constrained settings, comorbidities and the risk of SSI, evidence about surgical prophylaxis from low and middle-income countries, SSI gap between the developed and developing worlds and how to reduce resistance.

Summary: Antibiotic protocols can be adjusted to local and regional bacterial resistance profiles, taking into account the availability of antibiotics and cost limitations on each country in order to decrease the SSI risk.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Antibiotic Prophylaxis
  • Drug Resistance, Microbial*
  • Head / surgery*
  • Humans
  • Neck / surgery*
  • Poverty
  • Socioeconomic Factors
  • Surgical Wound Infection / drug therapy*
  • Surgical Wound Infection / etiology
  • Surgical Wound Infection / prevention & control*


  • Anti-Bacterial Agents