An adaptive pulmonary nodule detection algorithm

J Xray Sci Technol. 2020;28(3):427-447. doi: 10.3233/XST-200656.

Abstract

Recently, lung cancer has been paid more and more attention. People have reached a consensus that early detection and early treatment can improve the survival rate of patients. Among them, pulmonary nodules are the important reference for doctors to determine the lung health. With the continuous improvement of CT image resolution, more suspected pulmonary nodule information appears from the impact of chest CT. How to relatively and accurately locate the suspected nodule location from a large number of CT images has brought challenges to the doctor's daily diagnosis. To solve the problem that the original DBSCAN clustering algorithm needs manual setting of the threshold, this paper proposes a region growing algorithm and an adaptive DBSCAN clustering algorithm to improve the accuracy of pulmonary nodule detection. The image is roughly processed and ROI (Regions of Interest) region is roughly extracted by CLAHE transform. The region growing algorithm is used to roughly process the adjacent region's expansibility and the suspected region in ROI, and mark the center point in the region and the boundary point of its point set. The mean value of region range is taken as the threshold value of DBSCAN clustering algorithm. The center of the point domain is used as the starting point of clustering, and the rough set of points is used as the MinPts threshold. Finally, the clustering results are labeled in the initial CT image. Experiments show that the pulmonary nodule detection method proposed in this paper effectively improves the accuracy of the detection results.

Keywords: Pulmonary nodule detection; adaptive DBSCAN; region growing algorithm.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Humans
  • Lung / diagnostic imaging
  • Lung Neoplasms / diagnostic imaging*
  • Neural Networks, Computer
  • Radiographic Image Interpretation, Computer-Assisted / methods
  • Solitary Pulmonary Nodule / diagnostic imaging*
  • Tomography, X-Ray Computed / methods