Contrast enhanced ultrasonography (CEUS) to detect abdominal microcirculatory disorders in severe cases of COVID-19 infection: First experience

Clin Hemorheol Microcirc. 2020;74(4):353-361. doi: 10.3233/CH-209003.

Abstract

In the hands of experienced examiners, the contrast enhanced sonography (CEUS) offers the possibility to analyze dynamic microcirculatory disturbances in real time dynamically without any risk for kidneys and thyroid gland even in severe progressing disease bedside. Based on severe COVID-19 infections, first experiences with abdominal CEUS examinations are presented. In the stage of an imminent organ failure with significantly reduced kidney and liver function, CEUS can be used to show a narrowing of the organ-supplying arteries, as well as a delayed capillary filling of vessels near the capsule, a regional reduced parenchymal perfusion or an inflammatory hyperemia with capillary hypercirculation. It is possible to quickly rule out organ infarction and to dynamically record the mesenteric arterial and venous blood flow.

Keywords: COVID-19; Corona virus; contrast enhanced ultrasound sonography (CEUS); kidney; liver.

MeSH terms

  • Abdomen / blood supply*
  • Abdomen / diagnostic imaging
  • Aged
  • Betacoronavirus
  • COVID-19
  • Contrast Media / chemistry
  • Coronavirus Infections / diagnostic imaging*
  • Female
  • Humans
  • Inflammation / diagnostic imaging
  • Kidney / diagnostic imaging
  • Liver / diagnostic imaging
  • Male
  • Microcirculation*
  • Middle Aged
  • Pandemics
  • Perfusion
  • Pneumonia, Viral / diagnostic imaging*
  • Risk
  • SARS-CoV-2
  • Thyroid Gland / diagnostic imaging
  • Ultrasonography
  • Vascular Diseases / diagnostic imaging*

Substances

  • Contrast Media