One case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a low CD4+ T-cell count

doi:10.1016/j.ijid.2020.04.060

Case Reports

. 2020 Jul:96:148-150.

doi: 10.1016/j.ijid.2020.04.060. Epub 2020 Apr 23.

One case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a low CD4⁺ T-cell count

Maomao Wang¹, Limin Luo², Haiji Bu³, Hu Xia⁴

Affiliations

¹ Department of Neurosurgery, Changhai Hospital of the Second Military Medical University, Shanghai, China; Wuhan Huo Shen Shan Hospital, Wuhan, China.
² Department of Infectious Diseases, Airforce Hospital of Southern Theater Command, Guangzhou, China.
³ Pathology Department of Naval Medical Center of PLA, Shanghai, China.
⁴ Department of Pulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China. Electronic address: 1804066518@QQ.com.

PMID: 32335339
PMCID: PMC7194654
DOI: 10.1016/j.ijid.2020.04.060

Case Reports

One case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a low CD4⁺ T-cell count

Maomao Wang et al. Int J Infect Dis. 2020 Jul.

. 2020 Jul:96:148-150.

doi: 10.1016/j.ijid.2020.04.060. Epub 2020 Apr 23.

Authors

Maomao Wang¹, Limin Luo², Haiji Bu³, Hu Xia⁴

Affiliations

¹ Department of Neurosurgery, Changhai Hospital of the Second Military Medical University, Shanghai, China; Wuhan Huo Shen Shan Hospital, Wuhan, China.
² Department of Infectious Diseases, Airforce Hospital of Southern Theater Command, Guangzhou, China.
³ Pathology Department of Naval Medical Center of PLA, Shanghai, China.
⁴ Department of Pulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China. Electronic address: 1804066518@QQ.com.

PMID: 32335339
PMCID: PMC7194654
DOI: 10.1016/j.ijid.2020.04.060

Abstract

The ongoing outbreak of COVID-19 that began in Wuhan, China, become an emergency of international concern when thousands of people were infected around the world. This study reports a case simultaneously infected by SARS-Cov-2 and HIV, which showed a longer disease course and slower generation of specific antibodies. This case highlights that a co-infection of SARS-Cov-2 and HIV may severely impair the immune system.

Keywords: Antibody; COVID-19; HIV; SARS-Cov-2.

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Figures

**Figure 1**
Chest CT imaging changes. The first CT scan (A, C) showed bilateral diffuse ground glass appearance with some patchy consolidations. Another CT scan (B, D) performed after 9 days of treatment showed some improvement.

See this image and copyright information in PMC

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References

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1. Qin C., Zhou L., Hu Z. Dysregulation of immune response in patients with COVID-19 in Wuhan, China. Clin Infect Dis. 2020 (accepted article) - PMC - PubMed
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1. Li Z., Yi Y., Luo X. Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-Cov-2 infection diagnosis. J Med Virol. 2020 (accepted article) - PMC - PubMed

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[1] Leung G.M., Hedley A.J., Ho L.M. The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: an analysis of all 1755 patients. Ann Intern Med. 2004;141:662–673. - PubMed

[2] Leung G.M., Hedley A.J., Ho L.M. The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: an analysis of all 1755 patients. Ann Intern Med. 2004;141:662–673. - PubMed

[3] Qin C., Zhou L., Hu Z. Dysregulation of immune response in patients with COVID-19 in Wuhan, China. Clin Infect Dis. 2020 (accepted article) - PMC - PubMed

[4] Qin C., Zhou L., Hu Z. Dysregulation of immune response in patients with COVID-19 in Wuhan, China. Clin Infect Dis. 2020 (accepted article) - PMC - PubMed

[5] Huang C., Wang Y., Li X. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506. - PMC - PubMed

[6] Huang C., Wang Y., Li X. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506. - PMC - PubMed

[7] Lee H.K., Lee B.H., Seok S.H. Production of specific antibodies against SARS-coronavirus nucleocapsid protein without cross reactivity with human coronavirus 229E and OC43. J Vet Sci. 2010;11(2):165–167. - PMC - PubMed

[8] Lee H.K., Lee B.H., Seok S.H. Production of specific antibodies against SARS-coronavirus nucleocapsid protein without cross reactivity with human coronavirus 229E and OC43. J Vet Sci. 2010;11(2):165–167. - PMC - PubMed

[9] Li Z., Yi Y., Luo X. Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-Cov-2 infection diagnosis. J Med Virol. 2020 (accepted article) - PMC - PubMed

[10] Li Z., Yi Y., Luo X. Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-Cov-2 infection diagnosis. J Med Virol. 2020 (accepted article) - PMC - PubMed

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One case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a low CD4⁺ T-cell count

Affiliations

One case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a low CD4⁺ T-cell count

Authors

Affiliations

Abstract

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LinkOut - more resources

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