Association of Bleeding Scores and Platelet Transfusions With Platelet Counts and Closure Times in Response to Adenosine Diphosphate (CT-ADPs) Among Preterm Neonates With Thrombocytopenia

JAMA Netw Open. 2020 Apr 1;3(4):e203394. doi: 10.1001/jamanetworkopen.2020.3394.


This cohort study analyzes the association of closure time in response to adenosine diphosphate (CT-ADP) with bleeding score and the associations of platelet transfusions with change in platelet count, CT-ADP, and bleeding scores in preterm neonates with thrombocytopenia.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Diphosphate
  • Cohort Studies
  • Hemorrhage / epidemiology*
  • Hemorrhage / etiology
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Platelet Function Tests / statistics & numerical data*
  • Platelet Transfusion / statistics & numerical data*
  • Thrombocytopenia* / complications
  • Thrombocytopenia* / diagnosis
  • Thrombocytopenia* / epidemiology
  • Thrombocytopenia* / physiopathology


  • Adenosine Diphosphate