Exercise and Type 1 Diabetes

Adv Exp Med Biol. 2020:1228:107-121. doi: 10.1007/978-981-15-1792-1_7.


Diabetes mellitus (DM) is the most common endocrine and metabolic disease caused by absolute or insufficient insulin secretion. Under the context of an aging population worldwide, the number of diabetic patients is increasing year by year. Most patients with diabetes have multiple complications that severely threaten their survival and living quality. DM is mainly divided into type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). T1DM is caused by absolute lack of insulin secretion, so the current treatment for T1DM patients is exogenous insulin replacement therapy. At present, exercise therapy has been widely recognized in the prevention and treatment of diabetes, and regular aerobic exercise has become an important part of T1DM treatment. At the same time, exercise therapy is also used in conjunction with other treatments in the prevention and treatment of diabetic complications. However, for patients with T1DM, exercise still has the risk of hypoglycemia or hyperglycemia. T1DM Patients and specialist physician need to fully understand the effects of exercise on metabolism and implement individualized exercise programs. This chapter reviews the related content of exercise and T1DM.

Keywords: Diabetes mellitus; Exercise; Type 1 diabetes mellitus.

Publication types

  • Review

MeSH terms

  • Blood Glucose / metabolism
  • Diabetes Mellitus, Type 1* / metabolism
  • Diabetes Mellitus, Type 1* / prevention & control
  • Diabetes Mellitus, Type 1* / therapy
  • Exercise*
  • Humans
  • Insulin / metabolism


  • Blood Glucose
  • Insulin