From Genetics to Genomics: Facing the Liability Implications in Clinical Care

J Law Med Ethics. 2020 Mar;48(1):11-43. doi: 10.1177/1073110520916994.


Health care is transitioning from genetics to genomics, in which single-gene testing for diagnosis is being replaced by multi-gene panels, genome-wide sequencing, and other multi-genic tests for disease diagnosis, prediction, prognosis, and treatment. This health care transition is spurring a new set of increased or novel liability risks for health care providers and test laboratories. This article describes this transition in both medical care and liability, and addresses 11 areas of potential increased or novel liability risk, offering recommendations to both health care and legal actors to address and manage those liability risks.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Confidentiality
  • Delivery of Health Care / legislation & jurisprudence*
  • Delivery of Health Care / trends*
  • Disclosure
  • Genomics / legislation & jurisprudence*
  • Genomics / trends*
  • Health Insurance Portability and Accountability Act
  • Humans
  • Liability, Legal*
  • Malpractice
  • Privacy
  • United States