[Preliminary analysis of inheritance of scoliosis]

Genetika. 1988 Nov;24(11):2056-63.
[Article in Russian]


90 pedigrees (283 individuals) were used for statistical and segregation analysis of scoliosis inheritance. It was shown that inheritance of scoliosis may be described by the monogenic model with incomplete penetrance of heterozygotes, the latter being lower in men than in women. The monogenic model allows to perform correct predictions, the probability of incorrect prediction being about 0.1.

Publication types

  • English Abstract

MeSH terms

  • Female
  • Gene Frequency
  • Humans
  • Male
  • Models, Genetic*
  • Phenotype
  • Scoliosis / genetics*