Diagnosis and Management of Polycystic Ovary Syndrome in Adolescents

Pediatrics. 2020 May;145(Suppl 2):S210-S218. doi: 10.1542/peds.2019-2056J.

Abstract

Polycystic ovary syndrome (PCOS) is a common female reproductive disorder that often manifests during adolescence and is associated with disruptions in health-related quality of life. Prompt evaluation and clinical support after diagnosis may prevent associated complications and optimize overall health management. This article incorporates the most recent evidence and consensus guidelines to provide an updated review of the pathogenesis, clinical presentation, diagnostic evaluation, and management strategies for adolescents with this complex condition. We will review the recent international guidelines on PCOS; because the diagnosis of PCOS remains controversial, management of this condition is inconsistent. In 2019, PCOS remains a common, yet neglected, condition, in part, because of the lack of agreement around both diagnosis and management.

MeSH terms

  • Adolescent
  • Androgens / blood
  • Female
  • Follow-Up Studies
  • Guideline Adherence
  • Humans
  • Insulin / blood
  • Luteinizing Hormone / blood
  • Polycystic Ovary Syndrome / diagnosis*
  • Polycystic Ovary Syndrome / genetics
  • Polycystic Ovary Syndrome / psychology
  • Polycystic Ovary Syndrome / therapy
  • Quality of Life / psychology*
  • Risk Factors

Substances

  • Androgens
  • Insulin
  • Luteinizing Hormone