Will helminth co-infection modulate COVID-19 severity in endemic regions?

Nat Rev Immunol. 2020 Jun;20(6):342. doi: 10.1038/s41577-020-0330-5.

Abstract

As COVID-19 spreads through the world, most cases to date are in middle- and high-income nations. The impact on resource-poor nations remains unknown. Amongst many factors likely to affect the impact of COVID-19 in these areas, co-infections need to be considered. Here, we discuss whether the immunomodulatory effects of helminth infections may affect COVID-19 severity.

MeSH terms

  • Animals
  • Betacoronavirus
  • COVID-19
  • Coinfection
  • Coronavirus Infections / complications*
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / immunology
  • Coronavirus Infections / physiopathology
  • Endemic Diseases
  • Helminthiasis / complications*
  • Helminthiasis / epidemiology
  • Helminthiasis / immunology
  • Humans
  • Mice
  • Pandemics
  • Pneumonia, Viral / complications*
  • Pneumonia, Viral / epidemiology
  • Pneumonia, Viral / immunology
  • Pneumonia, Viral / physiopathology
  • SARS-CoV-2
  • Severity of Illness Index