Type I IFN immunoprofiling in COVID-19 patients

Sophie Trouillet-Assant; Sebastien Viel; Alexandre Gaymard; Sylvie Pons; Jean-Christophe Richard; Magali Perret; Marine Villard; Karen Brengel-Pesce; Bruno Lina; Mehdi Mezidi; Laurent Bitker; Alexandre Belot; COVID HCL Study group

doi:10.1016/j.jaci.2020.04.029

Type I IFN immunoprofiling in COVID-19 patients

J Allergy Clin Immunol. 2020 Jul;146(1):206-208.e2. doi: 10.1016/j.jaci.2020.04.029. Epub 2020 Apr 29.

Collaborators

COVID HCL Study group:
William Mouton, Guy Oriol, Christelle Compagnon, Laurence Generenaz, Valérie Cheynet, Florence Ader, Agathe Becker, Nicholas Benech, Pierre Chauvelot, Christian Chidiac, Anne Conrad, Tristan Ferry, Patrick Miailhes, Thomas Perpoint, Marielle Perry, Cécile Pouderoux, Sandrine Roux, Claire Triffault-Fillit, Florent Valour, Yonis Hodane, Louis Chauvelot, Paul Chabert, Judith Provoost, Guillaume David, Laure Folliet, Pierre Lecam, Geneviève Billaud, Maude Bouscambert, Vanessa Escuret, Emilie Frobert, Antonin Bal, Grégory Destras, Laurence Josset, Florence Morfin, Clément Munier, Martine Valette, Fabienne Venet, Lorna Garnier, Rémi Pescarmona, Christine Lombard, Thierry Walzer

Affiliations

¹ Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France. Electronic address: sophie.assant@chu-lyon.fr.
² International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in childrEn (RAISE), Lyon, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, Lyon, France.
³ International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Virology Department, Infective Agents Institute, National Reference Center for Respiratory Viruses, North Hospital Network, Lyon, France. Electronic address: alexandre.belot@chu-lyon.fr.
⁴ Joint Research Unit, Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.
⁵ Lyon University, CREATIS, CNRS UMR5220, Inserm U1044, INSA, Lyon, France; Intensive Care Unit, Hospices Civils de Lyon, Lyon, France.
⁶ International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Immunology Laboratory, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.
⁷ International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; Virology Department, Infective Agents Institute, National Reference Center for Respiratory Viruses, North Hospital Network, Lyon, France.
⁸ International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France; National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in childrEn (RAISE), Lyon, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, Lyon, France; Pediatric Nephrology, Rheumatology, Dermatology Unit, Hospices Civils de Lyon, Lyon, France.

No abstract available

Publication types

Letter

MeSH terms

Adult
Aged
Aged, 80 and over
Betacoronavirus
COVID-19
Coronavirus Infections / blood*
Coronavirus Infections / immunology*
Female
Humans
Interferon Type I / blood*
Interferon Type I / immunology*
Male
Middle Aged
Pandemics
Pneumonia, Viral / blood*
Pneumonia, Viral / immunology*
SARS-CoV-2

Substances

Interferon Type I