The relationship of gestational age to reserve albumin concentration for binding of bilirubin

J Perinatol. Winter 1988;8(1):17-8.


The authors studied bilirubin binding ability in the umbilical cord serum of 68 newborn infants ranging in gestational age from 18 to 42 weeks. There was no correlation between gestational age and the binding fraction (i.e., the ratio of the potential bilirubin binding concentration to the albumin concentration). Previous reports of the relationship between gestational age and bilirubin binding ability used bilirubin data derived from samples drawn at variable times after birth and probably reflect the unexplained effect of illness on bilirubin binding.

MeSH terms

  • Bilirubin / blood*
  • Fetal Blood / analysis
  • Gestational Age*
  • Humans
  • Infant, Newborn
  • Protein Binding
  • Regression Analysis
  • Serum Albumin / analysis*


  • Serum Albumin
  • Bilirubin