Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine

Open Forum Infect Dis. 2020 Mar 28;7(4):ofaa108. doi: 10.1093/ofid/ofaa108. eCollection 2020 Apr.


HIV-exposed, uninfected (HEU) infants receiving neonatal postexposure prophylaxis with zidovudine showed nonsignificant trends of lower CD4 and CD8 T cells as well as CD19 B cells than those who did not, suggesting toxicity that might impact the overall health of HEU children.

Keywords: HIV-exposed uninfected infants; adjusted mean difference; lymphocyte subsets; neonatal postexposure prophylaxis; zidovudine.